Periodontitis and Systemic Diseases. Группа авторов
bidirectional relationship. Odontology 2006;94: 10–21.
132. Duarte PM, Bezerra JP, Miranda TS, Feres M, Chambrone L, Shaddox LM. Local levels of inflammatory mediators in uncontrolled type 2 diabetic subjects with chronic periodontitis. J Clin Periodontol 2014;41:11–18.
133. Bastos AS, Graves DT, Loureiro AP, et al. Lipid peroxidation is associated with the severity of periodontal disease and local inflammatory markers in patients with type 2 diabetes. J Clin Endocrinol Metab 2012;97:E1353–E1362.
134. Polak D, Shapira L. An update on the evidence for pathogenic mechanisms that may link periodontitis and diabetes. J Clin Periodontol 2018;45:150–166.
135. Taylor JJ, Preshaw PM, Lalla E. A review of the evidence for pathogenic mechanisms that may link periodontitis and diabetes. J Periodontol 2013;84(4 Suppl):S113–S134.
136. Matthews JB, Wright HJ, Roberts A, Cooper PR, Chapple ILC. Hyperactivity and reactivity of peripheral blood neutrophils in chronic periodontitis. Clin Exp Immunol 2007;147:255–264.
137. Silva JAF, Lopes Ferrucci D, Peroni LA, et al. Periodontal disease-associated compensatory expression of osteoprotegerin is lost in type 1 diabetes mellitus and correlates with alveolar bone destruction by regulating osteoclastogenesis. Cells Tissues Organs 2012;196:137–150.
138. Liu R, Bal HS, Desta T, et al. Diabetes enhances periodontal bone loss through enhanced resorption and diminished bone formation. J Dent Res 2006;85:510–514.
139. Wu YY, Xiao E, Graves DT. Diabetes mellitus related bone metabolism and periodontal disease. Int J Oral Sci 2015;7:63–72.
140. Pacios S, Kang J, Galicia J, et al. Diabetes aggravates periodontitis by limiting repair through enhanced inflammation. FASEB J 2012;26:1423–1430.
141. Lumeng CN, Saltiel AR. Inflammatory links between obesity and metabolic disease. J Clin Invest 2011;121: 2111–2117.
142. Timar R, Timar B, Degeratu D, Serafinceanu C, Oancea C. Metabolic syndrome, adiponectin and proinflammatory status in patients with type 1 diabetes mellitus. J Int Med Res 2014;42:1131–1138.
143. Blüher M. Adipokines - removing road blocks to obesity and diabetes therapy. Mol Metab 2014;3:230–240.
144. Freitas Lima LC, Braga VA, do Socorro de França Silva M, et al. Adipokines, diabetes and atherosclerosis: an inflammatory association. Front Physiol 2015;6:304.
145. Deschner J, Eick S, Damanaki A, Nokhbehsaim M. The role of adipokines in periodontal infection and healing. Mol Oral Microbiol 2014;29:258–269.
146. Blüher M. Adipose tissue dysfunction in obesity. Exp Clin Endocrinol Diabetes 2009;117:241–250.
147. Van De Voorde J, Pauwels B, Boydens C, Decaluwé K. Adipocytokines in relation to cardiovascular disease. Metabolism 2013;62:1513–1521.
148. Hotamisligil GS. Mechanisms of TNF-α-induced insulin resistance. Exp Clin Endocrinol Diabetes 1999;107: 119–125.
149. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003;112:1796–1808.
150. Cildir G, Akincilar SC, Tergaonkar V. Chronic adipose tissue inflammation: all immune cells on the stage. Trends Mol Med 2013;19:487–500.
151. Palomer X, Salvadó L, Barroso E, Vázquez-Carrera M. An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy. Int J Cardiol 2013;168:3160–3172.
152. Schuett H, Luchtefeld M, Grothusen C, Grote K, Schieffer B. How much is too much? Interleukin-6 and its signalling in atherosclerosis. Thromb Haemost 2009;102: 215–222.
153. Skurk T, Alberti-Huber C, Herder C, Hauner H. Relationship between adipocyte size and adipokine expression and secretion. J Clin Endocrinol Metab 2007;92:1023–1033.
154. Hassan W, Ding L, Gao RY, Liu J, Shang J. Interleukin-6 signal transduction and its role in hepatic lipid metabolic disorders. Cytokine 2014;66:133–142.
155. Sabio G, Davis RJ. CJun NH2-terminal kinase 1 (JNK1): Roles in metabolic regulation of insulin resistance. Trends Biochem Sci 2010;35:490–496.
156. Tunes RS, Foss-Freitas MC, Da Rocha Nogueira-Filho G. Impact of periodontitis on the diabetes-related inflammatory status. J Can Dent Assoc 2010;76:a35.
157. Laubner K, Kieffer TJ, Lam NT, Niu X, Jakob F, Seufert J. Inhibition of preproinsulin gene expression by leptin induction of suppressor of cytokine signaling 3 in pancreatic β-cells. Diabetes 2005;54:3410–3417.
158. Brown JEP, Thomas S Digby JE, Dunmore SJ. Glucose induces and leptin decreases expression of uncoupling protein-2 mRNA in human islets. FEBS Lett 2002;513: 189–192.
159. Johnson RB, Serio FG. Leptin within healthy and diseased human gingiva. J Periodontol 2001;72:1254–1257.
160. Karthikeyan BV, Pradeep AR. Gingival crevicular fluid and serum leptin: Their relationship to periodontal health and disease. J Clin Periodontol 2007;34:467–472.
161. Shimada Y, Komatsu Y, Ikezawa-Suzuki I, Tai H, Sugita N, Yoshie H. The effect of periodontal treatment on serum leptin, interleukin-6, and C-reactive protein. J Periodontol 2010;81:1118–1123.
162. Zimmermann GS, Bastos MF, Dias Gonçalves TE, Chambrone L, Duarte PM. Local and circulating levels of adipocytokines in obese and normal weight individuals with chronic periodontitis. J Periodontol 2013;84: 624–633.