Ribosome-inactivating Proteins. Ricin and Related Proteins. Lappi Douglas
Ribosome-inactivating Proteins. Ricin and Related Proteins
Год выпуска: 0
Автор произведения: Lappi Douglas
Жанр: Прочая образовательная литература
Издательство: John Wiley & Sons Limited
isbn: 9781118846940
Краткое описание:
This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain.