Applied Organic Chemistry. Surya K. De
Thioether to Sulfone Thiol to Disulfide [23–25] Unsymmetrical Disulfide Reductive Amination Amine to Urea and Thiourea Urea Formation from Two Amines References
22 14 Synthesis of Some Drug Molecules References
23
15 Common Laboratory Methods
Acetylation of Alcohol (patent WO2013040068A2)
Deacetylation (patent WO2013040068A2)
Tosylation of Alcohol (patent US9399645B2)
Benzoylation of Alcohol (patent WO2019093776A1)
Pivaloylation of Alcohol (patent WO2019093776A1)
Silylation of Alcohol (patent WO1998008849A1)
Desilylation (patent WO1998008849A1)
Esterification (ester formation)
Ester Formation from Acid and Alcohol (patent US9399645B2)
Carboxylic Acid to Benzyl Ester (patent WO2019134765A1)
Hydrolysis (saponification) of Ester
Carboxylic Acid to Acid Chloride (patent US20070197544A1)
Acid Chloride to Amide (patent US20070197544A1)
Amide Bond Formation Using Carboxylic Acid and PBr3 (patent US20070197544A1)
Buchwald–Hartwig Amination (patent US20070197544A1)
Ester to Carboxylic Acid (patent WO2019134765A1)
Benzyl Ester to Carboxylic Acid (patent WO2019134765A1)
Boc‐ Protection of Amino Group (patent US20090054548A1)
Deprotection of Boc Group (patent US20090054548A1)
Sulfonation of Aromatic Compound (patent WO2002030878A1)
Nitration of Aromatic Compound (mild and noncorrosive conditions) (patent WO1994019310A1)
Nitration of Aromatic Compound (regular method)
Nitration of Aromatic Compound (regular method) (patent WO2016118450A1)
Reduction of Nitro Group (patent WO2018167800A1)
Reduction of Nitro Group by Hydrogenation (patent US6329380B1)
Reduction of Nitro Group Using Hydrazine Raney Nickel (patent US20070197544A1)
Reduction of Nitro Group Using Fe and NH4Cl (patent US20070197544A1)
Reduction of Ketone with NaBH4 (patent WO2013040068A2)
Reduction of Ester to Alcohol (patent US9399645B2)
Reduction of Ester to Alcohol with DIBAL‐H (patent WO2016037566A1)
Ester to Aldehyde (patent US20190337964A1)
Selective Oxidation of Primary Alcohol (patent WO2013040068A2)
Oxidation of Alcohol Using DMP
Oxidation of Primary Alcohol Using TEMPO (patent US10407378B2)
Benzylation of Phenol
Debenzylation by Hydrogenation (Patent WO1994028886A1)
Iodination of Aromatic Compound (patent US7951832B2)
Methylation of Phenol
Demethylation to Phenol (patent US6924310B2)
Bromide to O‐Benzyl (patent WO2019134765A1)
Tosylate to Fluoride (patent WO2019134765A1)
Iodide to Tosylate (patent WO2019134765A1)
Ozonolysis of Alkene (patent WO2013040068A2)
Asymmetric Dihydroxylation of Alkene (Sharpless Method) (WO2019093776A1)
Alcohol to Fluoride (WO2019134765A1)
Alcohol to Iodide (patent US9399645B2)
Alcohol to Bromide (patent WO2016037566A1)
Alcohol to Iodide via Tosylation (patent WO2016037566A1)
Alkene to Aldehyde (patent WO1998008849A1)
Amine to Azide via Diazotization (patent WO20030135050A1)
Azide to Amine (patent US6329380B1)
Reductive Amination (patent WO2005118525A1)
Asymmetric C‐Alkylation (patent WO2005118525A1)
Aldehyde to 1,1‐Difluoroalkane (WO2018167800A1)
Free Radical Reaction (patent WO2013040068A2)
Umpolung
Silylation of 1,3‐Dithiane (C‐Silylation) (Model reactions for education purpose only)
Alkylation on 2‐Diphenylmethyl‐1,3‐Dithiane