Medical Pharmacology at a Glance. Michael J. Neal

Medical Pharmacology at a Glance - Michael J. Neal


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      List of abbreviations

      Photo displaying oblong and round pills of various colors and sizes.5HT5‐hydroxytryptamine, serotoninACEangiotensin‐converting enzymeAChacetylcholineACTHadrenocorticotrophic hormoneADHantidiuretic hormoneADPadenosine diphosphateAIDSacquired immune deficiency syndromeAFatrial fibrillationARBangiotensin receptor blockerARTantiretroviral therapyBPblood pressurecAMPcyclic adenosine monophosphatecGMPcyclic guanosine monophosphateCOMTcatechol‐O‐methyltransferaseCOPDchronic obstructive pulmonary diseaseCOXcyclo‐oxygenaseCSFcerebrospinal fluidCNScentral nervous systemCYPcytochromeECFextra cellular fluidECGelectrocardiogramECTelectroconvulsive therapyFSHfollicle‐stimulating hormoneGABAγ‐aminobutyric acidGDPguanosine diphosphateGFRglomerular filtration rateGTNglyceryl trinitrateGTPguanosine triphosphateHIVhuman immunodeficiency virusHMG‐CoA3‐hydroxy‐3‐methylglutaryl coenzyme AIgA, E, G, Mimmunoglobulin A, E, G, MIl‐1b or 6interleukin‐1 beta or 6IP3inositol triphosphateIOPintraocular pressureKelelimination rateLDLlow‐density lipoproteinLSDlysergic acid diethylamideMAOmonoamine oxidaseNOnitric oxideNOSnitric oxide synthaseNE/NAnorepinephrine/noradrenalinePCIpercutaneous coronary interventionPETpositron emission tomographySANsinoatrial nodeSSRIsselective serotonin reuptake inhibitorsT1/T2mono/di‐iodothyronineTCAstricyclic antidepressantsT3tri‐iodothyronineT4thyroxineTNFtumour necrosis factorTSHthyroid‐stimulating hormoneTXA2thromboxane‐A2VLDLvery‐low‐density lipoproteinVTventricular tachycardia

Photo displaying oblong and round pills of various colors and sizes.

      Chapter 10 Ocular pharmacology

      Mydriatics and cycloplegics, e.g. tropicamide, cyclopentolate. Glaucoma, e.g. latanoprost, timolol. Age‐related macular degeneration (AMD), e.g. ranibizumab, bevacizumab.

      Chapter 11 Asthma, hay fever and anaphylaxis

      Asthma β‐agonists, e.g. salbutamol. Corticosteroids, e.g. inhaled beclomethasone. Muscarinic antagonist, e.g. ipratropium. Antihistamines, e.g. fexofenadine, cetirizine, chlorphenamine. Anaphylaxis, e.g. epinephrine, oxygen, chlorphenamine, hydrocortisone.

      Chapters 12 and 13 Gastrointestinal tract

      Peptic ulcer, reflux oesophagitis, e.g. ranitidine, omeprazole, lansoprazole, misoprostol. Diarrhoea, e.g. loperamide, codeine. Inflammatory bowel disease, e.g. prednisolone, sulfasalazine, azathioprine. Constipation, e.g. senna, lactulose. Antispasmodics, e.g. hyoscine butylbromide, mebeverine.

      Chapters 15–20 Cardiovascular system

      Hypertension: thiazide diuretics, e.g. bendroflumethiazide. ACE inhibitors, e.g. ramipril. ARBs, e.g. losartan. Calcium antagonists, e.g. amlodipine. Angina, e.g. glyceryl trinitrate, isosorbide mononitrate. β‐Blockers, e.g. bisoprolol. Calcium antagonists, e.g. amlodipine. Arrhythmias, e.g. adenosine, verapamil, digoxin, amiodarone. Chronic heart failure: ACE inhibitors, e.g. ramipril, lisinopril. ARBs, e.g. losartan, candesartan. β‐Blockers, e.g. carvedilol. Aldosterone antagonists, e.g. spironolactone, digoxin. Loop diuretics, e.g. furosemide. Anticoagulants, e.g. heparin, dalteparin, warfarin, dabigatran. Antiplatelet drugs, e.g. aspirin, clopidogrel, tirofiban, prasugrel. Thrombolytics, e.g. alteplase. Lipid‐lowering drugs: statins, e.g. simvastatin, atorvastatin.

      Chapters 5, 6 and 23–32 Nervous system

      Local anaesthetics, e.g. lidocaine, bupivacaine. General anaesthetics: intravenous, e.g. propofol. Inhalational, e.g. isoflurane, sevoflurane. Neuromuscular‐blocking drugs, e.g. suxamethonium, rocuronium. Premedication, e.g. diazepam, hyoscine, morphine. Anxiolytics, e.g. diazepam. Hypnotics, e.g. temazepam, zopiclone. Anticonvulsants, e.g. carbamazepine, valproate, lamotrigine, ethosuximide. Parkinson’s disease, e.g. levodopa, ropinirole, pramipexol. Antipsychotics, e.g. chlorpromazine, clozapine, risperidone, olanzapine. Antidepressants: SSRIs, e.g. citalopram, fluoxetine. Tricyclics, e.g. amitriptyline, lithium. Opioid analgesics, e.g morphine, diamorphine, fentanyl. NSAIDs, e.g. aspirin, ibuprofen, diclofenac, celecoxib. Antiemetics: dopamine antagonists, e.g. domperidone. Antihistamines, e.g. cyclizine, cinnarizine. 5HT3antagonists, e.g. ondansetron. Dependence: depressants, e.g. alcohol, barbiturates, morphine, diamorphine (heroin). Stimulants, e.g. cocaine, amphetamine, nicotine, cannabis, LSD.

      Chapters 33–36 Endocrine system

      Corticosteroids, e.g. prednisolone, dexamethasone, (bisphosphonates). Sex hormones and drugs: progestogens, e.g. desogestrel. Oestrogens, e.g. ethinylestradiol. Antithyroid drugs, e.g. carbimazole. Antidiabetic drugs, e.g. insulin, metformin. Sulphonylureas, e.g. glicazide. Glitazones, e.g. pioglitazone. Glucagon‐like peptide 2 agonists, e.g. exenatide, liraglutide. Dipeptidyl peptidase 4 inhibitors, e.g. saxagliptin. Sodium glucose co‐transporter‐2‐inhibitors (SGLT‐2 inhibitors), e.g. canagliflozin.

      Chapters 37–43 Infectious disease

      Antibacterial drugs, e.g. trimethoprim. Quinolones, e.g. ciprofloxacin. Metronidazole, e.g. rifampicin. Penicillins, e.g. benzylpenicillin, amoxicillin, flucloxacillin. Cephalosporins, e.g. cefalexin. Vancomycin. Aminoglycosides, e.g. gentamycin. Macrolides, e.g.


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