Cases in Medical Microbiology and Infectious Diseases. Melissa B. Miller
against the routine use of ribavirin in infants and children with lower respiratory tract illness because its efficacy in this population has not been proven. Randomized, controlled trials have demonstrated conflicting results. Further, ribavirin treatment is expensive. Treatment of RSV infection with ribavirin is reserved for immunosuppressed patients with severe RSV infection. Several reports have demonstrated that early administration of ribavirin significantly decreased lower respiratory tract illness, morbidity, and mortality in adult hematopoietic stem cell transplant recipients. Palivizumab cannot be used as a treatment for RSV; it only provides passive protection against infection.
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