Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition). William Gregory

Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition) - William Gregory


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href="#ulink_d5632163-5bb0-5c98-bfee-5989c0182e3e"> Introduction

       CIOMS I (1990): International Reporting of Adverse Drug Reactions

       CIOMS II (1992): International Reporting of Periodic Drug-Safety Update Summaries

       CIOMS III (1995 and 1998/1999): Guidelines for Preparing Core Clinical Safety Information on Drugs (1995), Including New Proposals for Investigator’s Brochures (1998/1999)

       CIOMS IV (1998): Benefit–Risk Balance for Marketed Drugs: Evaluating Safety Signals

       CIOMS V (2001): Current Challenges in Pharmacovigilance: Pragmatic Approaches

       CIOMS VI (2005): Management of Safety Information from Clinical Trials

       Regulatory Reporting and Communications of Safety Information from Clinical Trials

       CIOMS VII (2006): Development Safety Update Report (DSUR)

       CIOMS VIII (2010): Signal Detection (Points to Consider in Application of Signal Detection in Pharmacovigilance)

       CIOMS/WHO Working Group on Vaccine Pharmacovigilance (2012): Definitions and Applications of Terms for Vaccine Pharmacovigilance

       CIOMS IX (2014): Practical Approaches to Risk Minimization for Medicinal Products

       CIOMS X (2016): Evidence Synthesis and Meta-analysis

       CIOMS SMQs (2016): Development and Rational Use of Standardized MedDRA Queries: Retrieving Adverse Drug Reactions with MedDRA — Second Edition

       CIOMS (2017): Guide to Active Vaccine Safety Surveillance

       Chapter 13Where Data Reside

       Introduction

       FDA Adverse Event Reporting System

       FAERS Public Dashboard

       FAERS Quarterly Data Files

       Redacted ICSRs

       Clinical Trial Data

       The Uppsala Monitoring Centre

       VigiBase

       EMA EudraVigilance Database

       Motherisk

       Health Canada

       MHRA

       Teratology Data

       General Practice Research Database and Clinical Practice Research Datalink

       Other Registries and Databases

       Chapter 14Information Technology, Databases, and Computers

       Introduction

       Required Safety Database Functionality

       Data Entry

       Workflow

       Administration

       Vendor Support and Information Technology Issues

       Validation

       Labeling Functions

       Reporting Functions

       Data Export and Import

       Pharmacovigilance Functions

       Database Support

       Data Entry

       Data Transmission (E2B)

       E2B(R3)

       Safety Databases

       Database Migration

       Health Level 7

       Clinical Data Interchange Consortium

       Systematized Nomenclature of Medicine Clinical Terms

      


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