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Successful Drug Discovery
Volume 5
Edited by
János Fischer Christian Klein Wayne E. Childers
Editors
János Fischer
Richter Co., Plc.
Pharma Research
Gyömröi ut 19/21
1103 Budapest
Hungary
Christian Klein
Roche Innovation Center Zurich
Cancer Immunotherapy Discovery
Wagistrasse 10
8952 Schlieren
Switzerland
Wayne E. Childers
Temple University School of Pharmacy
Moulder Ctr. for Drug Discovery Res.
3307 N Broad Street
PA
United States
Cover
Supported by the
International Union of Pure and Applied Chemistry (IUPAC)
Chemistry and Human Health Division
PO Box 13757
Research Triangle Park, NC 2770‐3757
USA
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© 2021 WILEY‐VCH GmbH, Boschstr. 12, 69469 Weinheim, Germany
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Print ISBN: 978‐3‐527‐34754‐4
ePDF ISBN: 978‐3‐527‐82685‐8
ePub ISBN: 978‐3‐527‐82686‐5
oBook ISBN: 978‐3‐527‐82687‐2
Advisory Board Members
Jonathan Baell
(Monash University)
Gabriele Costantino
(University of Parma)
Jagath Reddy Junutula
(ModMab Therapeutics)
Kazumi Kondo
(Otsuka)
Roberto Pellicciari
(TES Pharma S.r.l.)
David Rotella
(Montclair State University)
Preface
The International Union of Pure and Applied Chemistry (IUPAC) supports the publication of the book series Successful Drug Discovery as projects. In these books, experts and key inventors describe and analyze different aspects of drug discovery.
The fifth volume of Successful Drug Discovery has the same structure as the previous volumes. New drug discoveries will be discussed in three parts: Part I: General Aspects, Part II: Drug Class Studies, and Part III: Case Studies encompassing both small‐molecule drugs and biologics.
The