Successful Drug Discovery, Volume 5. Группа авторов

Successful Drug Discovery, Volume 5 - Группа авторов


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      Successful Drug Discovery

      Volume 5

       Edited by

       János Fischer Christian Klein Wayne E. Childers

Logo: Wiley

       János Fischer

      Richter Co., Plc.

      Pharma Research

      Gyömröi ut 19/21

      1103 Budapest

      Hungary

       Christian Klein

      Roche Innovation Center Zurich

      Cancer Immunotherapy Discovery

      Wagistrasse 10

      8952 Schlieren

      Switzerland

       Wayne E. Childers

      Temple University School of Pharmacy

      Moulder Ctr. for Drug Discovery Res.

      3307 N Broad Street

      PA

      United States

       Cover

      Supported by the

      International Union of Pure and Applied Chemistry (IUPAC)

      Chemistry and Human Health Division

      PO Box 13757

      Research Triangle Park, NC 2770‐3757

      USA

      All books published by Wiley‐VCH are carefully produced. Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedural details or other items may inadvertently be inaccurate.

       Library of Congress Card No.:

      applied for

       British Library Cataloguing‐in‐Publication Data

      A catalogue record for this book is available from the British Library.

       Bibliographic information published by the Deutsche Nationalbibliothek

      The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data are available on the Internet at <http://dnb.d-nb.de>.

      © 2021 WILEY‐VCH GmbH, Boschstr. 12, 69469 Weinheim, Germany

      All rights reserved (including those of translation into other languages). No part of this book may be reproduced in any form – by photoprinting, microfilm, or any other means – nor transmitted or translated into a machine language without written permission from the publishers. Registered names, trademarks, etc. used in this book, even when not specifically marked as such, are not to be considered unprotected by law.

      Print ISBN: 978‐3‐527‐34754‐4

      ePDF ISBN: 978‐3‐527‐82685‐8

      ePub ISBN: 978‐3‐527‐82686‐5

      oBook ISBN: 978‐3‐527‐82687‐2

       Jonathan Baell

      (Monash University)

       Gabriele Costantino

      (University of Parma)

       Jagath Reddy Junutula

      (ModMab Therapeutics)

       Kazumi Kondo

      (Otsuka)

       Roberto Pellicciari

      (TES Pharma S.r.l.)

       David Rotella

      (Montclair State University)

      The International Union of Pure and Applied Chemistry (IUPAC) supports the publication of the book series Successful Drug Discovery as projects. In these books, experts and key inventors describe and analyze different aspects of drug discovery.

      The fifth volume of Successful Drug Discovery has the same structure as the previous volumes. New drug discoveries will be discussed in three parts: Part I: General Aspects, Part II: Drug Class Studies, and Part III: Case Studies encompassing both small‐molecule drugs and biologics.

      The


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