Snyder and Champness Molecular Genetics of Bacteria. Tina M. Henkin
and S Recombinases Group II Mobile Introns: Elements that Move Using an RNA Intermediate Importance of Transposition and Site-Specific Recombination in Bacterial Adaptation
17 9 Molecular Mechanisms of Homologous Recombination Homologous Recombination and DNA Replication in Bacteria The Molecular Basis for Recombination in E. coli Recombination between Different DNAs in Bacteria Recombineering: Gene Replacements in E. coli with Phage λ Recombination Functions
18 10 DNA Repair and Mutagenesis Evidence for DNA Repair Specific Repair Pathways General Repair Mechanisms DNA Damage Tolerance Mechanisms Summary of Repair Pathways in E. coli Bacteriophage Repair Pathways
19 11 Regulation of Gene Expression: Genes and Operons Transcriptional Regulation in Bacteria Negative Regulation of Transcription Initiation Positive Regulation of Transcription Initiation Regulation by Transcription Attenuation Regulation of mRNA Degradation Regulation of Translation Posttranslational Regulation Why Are There So Many Mechanisms of Gene Regulation?
20 12 Global Regulation: Regulons and Stimulons Carbon Catabolite Regulation Regulation of Nitrogen Assimilation Regulation of Ribosome Components and tRNA Synthesis Ribosomal Protein Gene Regulation Stress Responses in Bacteria Iron Regulation in E. coli Regulation of Virulence Genes in Pathogenic Bacteria Developmental Regulation: Sporulation in B. subtilis
21 13 Genomes and Genomic Analysis The Bacterial Genome DNA Sequencing Barriers to Horizontal Transfer: Genome Gatekeepers and the Molecular Biologist’s Toolkit
22 Glossary
23 End Papers
24 Index
List of Illustrations
1 IntroductionFigure 1 A molecular tree of life capturing diversity using ribosomal proteins...
2 Chapter 1Figure 1.1 Schematic drawing of the Watson-Crick structure of DNA, showing the...Figure 1.2 Chemical structures of deoxyribonucleotides, showing the bases and ...Figure 1.3 (A) Schematic drawing of a DNA chain, showing the 3′-to-5′ attachme...Figure 1.4 The two complementary base pairs found in DNA. Two hydrogen bonds f...Figure 1.5 The pathways for synthesis of deoxynucleotides from ribonucleotides...Figure 1.6 Features of DNA. (A) Polymerization of the deoxynucleotides during ...Figure 1.7 Functions of the primer and template in DNA replication. (A) The DN...Figure 1.8 Discontinuous synthesis of one of the two strands of DNA during chr...Figure 1.9 DNA polymerase I can remove an RNA primer by using strand displacem...Figure 1.10 “Trombone” model for how both the leading strand and lagging stran...Figure 1.11 Mistakes in base pairing can lead to changes in the DNA sequence c...Figure 1.12 Editing function of DNA polymerase. (A) A G is mistakenly placed o...Figure 1.13 Physical blocks on template DNAs. (A) When DNA polymerase III stal...Figure 1.14 Structure of the origin of chromosomal replication (oriC) region o...Figure 1.15 Initiation of replication at the Escherichia coli origin (oriC) re...Figure 1.16 Termination of chromosome replication in Escherichia coli. (A) The...Figure 1.17 Model of the way in which chromosome translocation by FtsK coordin...Figure 1.18 Model of the way in which unwinding of the template DNA strands ca...Figure 1.19 Model of the way in which chromosome decatenation by topoisomerase...Figure 1.20