Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition). William Gregory

Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition) - William Gregory


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Interactions

       Frequency

       Communication

       Chapter 20Product Quality Issues

       Introduction

       Counterfeiting

       Frequently Asked Question

       Chapter 21AE Volume, Quality, Good Documentation Procedures, and Medical Records

       Introduction

       Archiving

       Record Retention Times

       Good Documentation Practices

       Chapter 22Seriousness, Expectedness, and Causality

       Seriousness

       Expectedness

       Relatedness (Causality)

       Methodology

       Global Introspection

       Algorithms

       Comment

       Health Authority Guidance and Requirements

       United States FDA

       European Union

       CIOMS I Assessment of Causality

       Uppsala Monitoring Centre (WHO)

       Judgment of Cases When Received Versus at the Time of Periodic Reporting and Signaling

       Summary and Comments

       Chapter 23Coding of Adverse Events and Drug Names

       Introduction

       AR/AE Coding

       MedDRA

       Regulatory Status

       MedDRA in Practice

       Standardized MedDRA Queries (SMQs)

       Training

       Systematized Nomenclature of Medicine — Clinical Terms

       AE Severity Coding

       Drug Names and Drug Dictionaries

       Multiple Names and Name Changes

       WHODrug Global

       EudraVigilance Medicinal Product Dictionary

       Future

       Frequently Asked Question

       Chapter 24Expedited and Aggregate Reporting in Clinical Trials

       Expedited Reporting

       Clinical Trial Reporting

       United States Requirements for Expedited IND Reports

       Expedited IND Reports (Alert Reports, 7-Day and 15-Day IND Reports)

       IND Annual Reports

       Other Clinical Trial (IND) Reporting Issues

       European Union Requirements

       Expedited Reporting in Clinical Trials

       Development Safety Update Reports

       When to Start Collecting Serious AEs in Trials

       Canadian Requirements

       Elsewhere

       Bottom Line

      


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