Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition). William Gregory

Cobert's Manual Of Drug Safety And Pharmacovigilance (Third Edition) - William Gregory


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Liaison to External Organizations/Drug Safety Intelligence

       PV Worker Education, Skills, and Profile

       Education

       Skills

       Profile

       Frequently Asked Question

       Chapter 32How an Individual Case Safety Report (ICSR) is Handled from Start to Finish

       Introduction

       AE Sources and Arrival in the Safety Department

       Triage

       Database Entry

       Quality Review

       Follow-Up

       Medical Review

       Case Closure

       Case Distribution and Transmission

       Tracking

       Investigator Notification

       15 Calendar Days and Day 0 versus Day 1

       Chapter 33PV Quality System

       Introduction

       Chapter 34Training

       Introduction

       Organizational Structure and Site Information

       Computer, Forms, Electronic, and Print Resources

       What is Pharmacovigilance?

       Corporate and Drug Safety SOPs, Working Documents, Guidelines, and Manuals

       Medical Dictionary for Regulatory Activities (MedDRA®) and Other Dictionaries

       Safety Database

       Workflow

       Partner and CRO Interactions

       Signaling and Pharmacovigilance

       Academic Training

       Other External Training

       Chapter 35Audits and Inspections

       The Basics

       Scope of the Audit

       How an Inspection Flows

       Findings

       Penalties

       Common Inspection Findings

       The Response to the Inspection or Audit

       The Corrective Action Preventive Action Plan (CAPA)

       FDA Safety Inspections

       Comments on EMA and MHRA Inspections

       Quality Systems and Inspection Preparation in Companies

       Key Documents

       Summary and Comments

       Chapter 36Pharmacovigilance System Master File

       Introduction

       Pharmacovigilance System Master File (Guideline on Good

       Pharmacovigilance Practice Module II)

       Comment

       Chapter 37Ethical Issues and Conflicts of Interest

       Introduction

      


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