Catalytic Asymmetric Synthesis. Группа авторов

Catalytic Asymmetric Synthesis - Группа авторов


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2.66) [137]. Chiral Ir catalyst bearing phosphate counteranion was generated.

      Source: Based on [133].

Schematic illustration of transition state of the transfer hydrogenation with Hantzsch ester. Schematic illustration of transfer hydrogenation of benzoxazine using DHPD.

      Source: Based on [136].

      Source: Based on [137].

Schematic illustration of transfer hydrogenation of N-alkyl ketimines (a), reductive condensation of N-H ketimines (b), and transfer hydrogenation of HCl salt of N-H ketimines (c) [140].

      Source: Based on [138]

      ), reductive condensation of N‐H ketimines (b) (

      Source: Based on [139]

      ), and transfer hydrogenation of HCl salt of N‐H ketimines (c) [140].

Schematic illustration of transfer hydrogenation of ketimines by benzothiazoline.

      Source: Based on [141].

Schematic illustration of results of the transfer hydrogenation of ketimines by benzothiazoline.

      Subsequently, Akiyama reported a self‐redox strategy for the oxidative kinetic resolution of indolines to furnish 2‐aryl indolines with 87–99% ee using salicyl aldehyde derivative as the preresolving reagent in place of ketimine catalyzed by CPA 6t, bearing bulky 9‐anthryl‐2,6‐diisopropylphenyl group at 3,3′‐positions. Iminium ion intermediate 31, which was formed by the condensation of indoline with salicyl aldehyde derivative, was hydrogenated from the 2‐aryl indoline (Scheme 2.68c) [154].

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