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Actinomyces spp.
Anaerobic, Gram-positive bacilli
Endogenous
PIDa associated with intrauterine device usage
Aerococcus spp.
Catalase-negative, Gram-positive cocci
Endogenous
Community- or health care-associated UTIb
Bacteroides fragilis
Anaerobic, Gram-negative bacillus
Endogenous
Pelvic abscess
Chlamydia trachomatis
Obligate intracellular pathogen (does not Gram stain)
Direct sexual contact
Urethritis, cervicitis, PID
Enterobacter spp.
Lactose-fermenting, Gram-negative bacilli
Endogenous
Community- or health care-associated UTI
Enterococcus spp.
Catalase-negative, Gram-positive cocci
Endogenous
Health care-associated UTI
Escherichia coli
Lactose-fermenting, Gram-negative bacillus
Endogenous
Community- or health care-associated UTI
Haemophilus ducreyi
Fastidious, pleiomorphic, Gram-negative bacillus
Direct sexual contact
Chancroid (painful genital ulcer)
Klebsiella pneumoniae
Lactose-fermenting, Gram-negative bacillus
Endogenous
Community- or health care-associated UTI
Morganella morganii
Lactose-nonfermenting, Gram-negative bacillus
Endogenous
Community- or health care-associated UTI
Mycoplasma hominis
Lacks a cell wall (does not Gram stain)
Endogenous; direct sexual contact
Pyelonephritis, PID
Neisseria gonorrhoeae
Gram-negative, intracellular diplococcus
Direct sexual contact
Urethritis, cervicitis, PID
Proteus mirabilis
Lactose-nonfermenting, swarming, Gram-negative bacillus
Endogenous
Community- or health care-associated UTI
Pseudomonas aeruginosa
Lactose-nonfermenting, Gram-negative bacillus
Catheterization
Health care-associated UTI
Staphylococcus saprophyticus
Catalase-positive, Gram-positive coccus
Endogenous
Community-associated UTI
Treponema pallidum
Spirochete (does not Gram stain)
Direct sexual contact; vertical, mother to child
Chancre (painless genital ulcer); primary, secondary, tertiary syphilis; neonatal syphilis
Ureaplasma urealyticum
Lacks a cell wall (does not Gram stain)
Endogenous; direct sexual contact
Urethritis, urethroprostatitis, epididymitis, chorioamnionitis
Fungi
Candida spp.
Yeasts with pseudohyphae
Endogenous
Vaginitis, health care-associated UTI, balanitis
Parasites
Phthirus pubis
Crab lice
Direct sexual contact
Pubic hair infestation
Trichomonas vaginalis
Protozoan
Direct sexual contact
Vaginitis
Viruses
Adenoviruses
Nonenveloped DNA viruses
Exogenous exposure
Hemorrhagic cystitis
Herpes simplex viruses (HSV-1 and -2)
Enveloped DNA viruses
Direct sexual contact; vertical, mother to child
Recurrent genital ulcers, fetal/neonatal infections, encephalitis
Human immunodeficiency viruses (HIV-1 and -2)
Retroviruses
Direct sexual contact; blood and body fluids; vertical, mother to child
AIDS, neonatal infection, dementia
Human papillomavirus
Nonenveloped DNA virus
Direct sexual contact
Genital warts, cervical and anal carcinoma
a PID, pelvic inflammatory disease.
b UTI, urinary tract infection.
CASE 1
The patient was a 19-year-old female with a history of a urinary tract infection (UTI) 4 months prior to admission for which she was treated with oral ampicillin
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