Bacterial Pathogenesis. Brenda A. Wilson
Bacterial
Pathogenesis
Fourth Edition
Bacterial
Pathogenesis
A Molecular Approach
Brenda A. Wilson
Department of Microbiology
University of Illinois at Urbana-Champaign
Urbana-Champaign, Illinois
Malcolm E. Winkler
Department of Biology
Indiana University
Bloomington, Indiana
Brian T. Ho
Institute of Structural and Molecular Biology
University College London and Birkbeck, University of London
London, United Kingdom
Washington, DC
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Library of Congress Cataloging-in-Publication Data
Names: Wilson, Brenda A., author. | Winkler, Malcolm E, author. | Ho, Brian T. (Brian Thomas), author. | Salyers, Abigail A. Bacterial pathogenesis.
Title: Bacterial pathogenesis : a molecular approach / Brenda A. Wilson, Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, Malcolm E. Winkler, Department of Biology, Indiana University, Bloomington, Indiana, Brian T. Ho, Institute of Structural and Molecular Biology, University College London and Birkbeck, University of London, London, United Kingdom.
Description: Fourth edition. | Washington, DC : ASM Press, [2019] | Revised and updated edition of the work originally authored by Abigail Salyers and Dixie Whitt.
Identifiers: LCCN 2019017126 (print) | LCCN 2019018854 (ebook) | ISBN 9781683672883 (eBook) | ISBN 9781555819408 (pbk.)
Subjects: LCSH: Bacterial diseases—Pathogenesis. | Molecular microbiology.
Classification: LCC QR201.B34 (ebook) | LCC QR201 .B34 S24 2019 (print) | DDC 579.3/165—dc23
LC record available at https://lccn.loc.gov/2019017126
All Rights Reserved
Printed in Canada
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doi:10.1128/9781555819415
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Illustrations and illustration concepting: Patrick Lane, ScEYEnce Studios
Cover and interior design: Debra Naylor, Naylor Design, Inc.
Cover image: Antibiotic (streptomycin) molecules being expelled out of a bacterium through the TolC efflux-pump. 3d rendering. Image courtesy of Juan Gaertner/Science Photo Library, used with permission. Based on Murakami S, Nakashima R, Yamashita E, Yamaguchi A. 2002. Nature 419:587–593.
To Abigail A. Salyers and Dixie D. Whitt
In recognition of their intrepid vision and leadership that forged the foundation of this fascinating exploration of the field of bacterial pathogenesis
Herein, their legacy lives on.
Contents
CHAPTER 1 The Power of Bacteria
Why Are Bacteria So Much in the Public Health Spotlight Nowadays?
Bacteria, a Formidable Ancient Life Form
Pressing Current Infectious Disease Issues
Emerging and Reemerging Infectious Diseases
Foodborne and Waterborne Infections
Modern Medicine as a Source of New Diseases
Postsurgical and Other Wound Infections
Surveillance: An Early Warning System
Making Hospitals Safe for Patients
And Now for Some Good News: You’ve Got a Bacterial Infection!
The Helicobacter pylori Revolution