Analfissur. Franz Raulf
M, Alexander-Williams J, Buchmann P et al.: A randomized controlled trial to compare anal dilatation with lateral subcutaneous sphincterotomy for anal fissure. Dis Colon Rectum 22, 308–311, 1979
Mazier WP: An evaluation of the surgical treatment of anal fissure. Dis Colon Rectum 15, 222–227, 1972
Mentes BB, Irkörücü O, Akin M et al.: Comparison of botulinum toxin injection and lateral sphincterotomy for the treatment of chronic anal fissure. Dis Colon Rectum 46, 232–237, 2003
Pascual M, Pera M, Courtier R et al.: Endosonographic and manometric evaluation of internal anal sphincter in patients with chronic anal fissure and its correlation with clinical outcome after topic glyceryl trinitrate. Int J Coloproctol Dis 22, 963–967, 2007
Pernikoff BJ, Eisenstat TE, Rubin RJ et al.: Reappraisal of partial lateral internal sphincterotomy. Dis Colon Rectum 37, 1291–1295, 1994
Prohm P: Analyse der prä- und postoperativen Kontinenzfunktion nach lateraler Sphinkterotomie am Beispiel der chronischen Analfissur. Kontinenz 2, 120–124, 1993
Richard CS, Gregoire R, Plewes EA et al.: Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure. Dis Colon Rectum 43, 1048–1057, 2000
Stürmlinger M: Funktionelle Ergebnisse der lateralen Sphinkterotomie im Rahmen der Behandlung der chronischen Analfissur. Med. Diss. Düsseldorf, 1986
Vafai M, Mann CV: Ambulante geschlossene laterale interne Sphinkterotomie in der Behandlung von Analfissuren. coloproctology 9, 49–53, 1987
Wolff J: Die Analfissur und ihre chirurgische Therapie: eine Nachuntersuchung des Patientengutes der Chirurgischen Universitätsklinik Bonn-Venusberg von 1979–1984. Med. Diss. Bonn, 1986
3.5. Krankheitsdauer
Analfissurpatienten sind offenbar sehr duldsam, denn sie ertragen ihre Schmerzen erstaunlich lange, bevor sie sich in Behandlung begeben. In mehreren Studien wurde die Zeitdauer bis zum Therapiebeginn recherchiert. Bei 491 Patienten in acht Studien, die mit Glyceryltrinitrat (GTN) behandelt wurden, betrug diese Leidenszeit 2 bis 240 Monate, in sieben Botulinumtoxin-Studien (BTX) mit 405 Patienten 3 bis 94 Monate. Bei 842 Patienten (in neun Studien), die sich einer Sphinkterotomie unterzogen, bestanden die Symptome über eine Dauer von 1 bis 96 Monaten. Im Durchschnitt betrug die Anamnesedauer mehr als zehn Monate.
Tab. 5 Dauer der Beschwerden bis zur GTN-Therapie
Tab. 6 Dauer der Beschwerden bis zur BTX-Therapie
Tab. 7 Dauer der Beschwerden bis zur Sphinkterotomie
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