Epitome of the Pharmacopeia of the United States and the National Formulary. Torald Hermann Sollmann

Epitome of the Pharmacopeia of the United States and the National Formulary - Torald Hermann Sollmann


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N.F. III).—Salicylic acid (10%), and creosote (20%) in yellow wax and benzoinated suet.

      Pulvis Talci Compositus (Pulv. Talc. Co.), Compound Powder of Talc, N.F. (Boro-Salicylated Powder of Talc).—Salicylic acid (3%), boric acid (10%) and talc.

      Uses: Toilet powder, used for local sweating.

      Stili Acidi Salicylici Dilubiles (Stil. Acid. Salicyl. Dilub.), Salicylic Acid Pencil, N.F.—Salicylic acid (10%) with tragacanth, starch, white dextrin and sugar.

      Uses: For the application of salicylic acid to limited areas.

      Acidum Stearicum (Acid. Stear.), Stearic Acid, U.S.P.—Obtained from fats.

      A white, hard, unctuous, odorless and tasteless substance. Soluble in alcohol (1:21) and in chloroform (1:2), but insoluble in water.

      Uses: Used in making glycerin suppositories.

      Acidum Sulphuricum (Acid. Sulph.), Sulphuric Acid, U.S.P.—H2SO4 (about 94%).

      A colorless, odorless, corrosive liquid. Miscible with water or alcohol with evolution of much heat.

      Action and Uses: Similar to those of hydrochloric acid. Externally, the dilute acid is used as astringent.

      Acidum Sulphuricum Aromaticum (Acid. Sulph. Arom.), Aromatic Sulphuric Acid, U.S.P.—A mixture, containing free sulphuric acid and ethylsulphuric acid equivalent to about 20 per cent. of H2SO4 in alcohol, flavored with ginger and cinnamon. Absolute alcohol content about 85 per cent.

      A clear, reddish-brown liquid with an aromatic odor.

      Dosage: 1 Cc. or 15 minims, well diluted.

      Acidum Sulphuricum Dilutum (Acid. Sulph. Dil.), Diluted Sulphuric Acid, U.S.P.—H2SO4 (about 10%).

      Dosage: 1 Cc. or 15 minims (U.S.P.), well diluted.

      *Acidum Tannicum (Acid. Tann.), Tannic Acid, U.S.P. (Gallotannic Acid, Tannin).—Usually obtained from nutgalls.

      A yellowish-white to light brown powder, odorless or having a faint, characteristic odor and a strongly astringent taste. Freely soluble in glycerin (1:1) and very soluble in water and in alcohol. Incompatible with soluble preparations of iron.

      Action and Uses: Astringent; local hemostatic; antidote for certain alkaloidal and metallic poisons.

      Dosage: 0.5 Gm. or 8 grains (U.S.P.).

      Collodium Stypticum (Collod. Stypt.), Styptic Collodion, N.F.—Tannic acid (20%) and flexible collodion. There is no advantage in applying tannin as collodion.

      *Glyceritum Acidi Tannici (Glycer. Acid. Tann.), Glycerite of Tannic Acid, U.S.P. (Glycerite of Tannin).—Tannic acid (20%) in glycerin.

      Dosage: 2 Cc. or 30 minims (U.S.P.).

      Trochisci Acidi Tannici (Troch. Acid. Tann.), Troches of Tannic Acid, U.S.P.—Each troche contains tannic acid (0.06 Gm. or 1 grain), with sugar and tragacanth, flavored with orange flower.

      Unguentum Acidi Tannici (Ung. Acid. Tann.), Ointment of Tannic Acid, U.S.P.—Tannic acid (20%), in glycerin and ointment.

      Acidum Tartaricum (Acid. Tart.), Tartaric Acid, U.S.P.—Obtained from wine lees or argol.

      A white, odorless powder, with an acid taste. Very soluble in water (1:0.75) and in alcohol (1:3.3).

      Action and Uses: Mild acid; used in the manufacture of effervescent salts.

      Dosage: 0.5 Gm. or 8 grains, diluted.

      Acidum Trichloraceticum (Acid. Trichloracet.), Trichloracetic Acid, U.S.P.—CCl3.COOH.

      Colorless, deliquescent crystals with a slight characteristic odor. Miscible with water and with alcohol.

      Action and Uses: Caustic, for the removal of warts and other skin blemishes. Used also as local hemostatic.

      Aconitina (Aconitin.), Aconitine, U.S.P.—An alkaloid obtained from aconite.

      A white, odorless powder. Very slightly soluble in water, soluble in alcohol (1:28) and in ether (1:65).

      Action and Uses: Similar to those described under aconite. As several alkaloidal preparations of aconite, of varying activity, are sold under the name of aconitine, its use is not advisable.

      Dosage: 0.15 mg. or ¼00 grain (U.S.P.).

      Oleatum Aconitinae (Oleat. Aconitin.), Oleate of Aconitine, N.F.—Aconitine (2%) in oleic acid and olive oil.

      Uses: Without advantage over aconite preparations for external application.

      *Aconitum (Aconit.), Aconite, U.S.P. (Monkshood, Aconite Root, Aconiti Tuber, P.I.).—A tuberous root, yielding about 0.5 per cent. of ether-soluble alkaloids; also assayed biologically. Physicians should specify preparations that have been assayed biologically, since the alkaloidal assay is not a reliable index of activity.

      Action and Uses: Slows the pulse and lowers the blood pressure, but this action in therapeutic doses is uncertain. Used in the treatment of febrile colds; also for counter-irritation, in the form of the tincture. Used also as a local anesthetic, and by some still believed to be useful in the treatment of the symptoms arising from excessive cardiac hypertrophy. Toxic symptoms may occur from local absorption.

      Dosage: 0.03 Gm. or ½ grain (U.S.P.); not used as such.

      Extractum Aconiti (Ext. Aconit.), Extract of Aconite, U.S.P. (Powdered Extract of Aconite).—Yields about 2 per cent. of ether-soluble alkaloids. Biologically assayed by producing death in the guinea-pig.

      Dosage: 0.01 Gm. or ⅙ grain (U.S.P.). Physicians who prescribe extract of aconite should specify the biologically assayed product.

      Fluidextractum Aconiti (Fldext. Aconit.), Fluidextract of Aconite, U.S.P.—Aconite (100%), yielding about 0.5 per cent. of alkaloids. Absolute alcohol content about 70 per cent. Biologically assayed by producing death in the guinea-pig.

      Dosage: 0.03 Cc. or ½ minim (U.S.P.). Physicians who prescribe fluidextract of aconite should specify the biologically assayed product. Best to use the tincture.

      Linimentum Aconiti et Chloroformi (Lin. Aconit. et Chlorof.), Liniment of Aconite and Chloroform, N.F.—Fluidextract of aconite (4.5%), in alcohol, chloroform and soap liniment.

      *Tinctura Aconiti (Tr. Aconit.), Tincture of Aconite, U.S.P. (Aconiti Tinctura, P.I.).—Aconite (10%) yielding about 0.05 per cent. of alkaloids, in alcohol and water. Alkaloidal assay unreliable. Biologically assayed by producing death in the guinea-pig. Absolute alcohol content about 65 per cent.

      Dosage: 0.3 Cc. or 5 minims (U.S.P.). Physicians should specify the biologically assayed product.

      *Adeps (Adeps), Lard, U.S.P.

      Insoluble in water, and only slightly soluble in alcohol.

      Action and Uses: Basis for ointments. Used particularly when absorption is desired.

      *Adeps Benzoinatus (Adeps Benz.), Benzoinated Lard, U.S.P.—Somewhat antiseptic and less liable to rancidity than ordinary lard.

      Unguentum (Ung.), Ointment, U.S.P. (Simple Ointment).—White wax (20%) and benzoinated lard.

      Adeps Lanae (Adeps Lan.), Wool Fat, U.S.P. (Anhydrous Lanolin).—Purified wool fat, freed from water.

      Insoluble in but miscible with about twice its weight of water; sparingly soluble in cold alcohol.

      Action and Uses: Basis for ointments; because of its tenacious consistency, should be mixed with some other base.

      *Adeps Lanae Hydrosus (Adeps Lan. Hyd.), Hydrous Wool Fat, U.S.P. (Lanolin).—Wool


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